Sentence examples for variants to confer from inspiring English sources

We found co-occurrence of ACE indel and AT1R c.1166A > C variants to confer risk for small-vessel occlusion type stroke in a Hungarian population [ 55].

An elaborate and poorly understood mechanism of coordinated silencing of the VAR genes is combined with rare epigenetic switches to other variants to confer an ever-shifting antigenic makeup.

This F2 20210G>A polymorphism has been claimed to interact with a common F13A1 Val34Leu (rs5985) variant to confer a greatly increased risk of myocardial infarction (Butt et al. 2003).

The association was not further established in the replication study of young patients with early-onset MI, which may indicate that other co-factors are necessary for this variant to confer a risk increase.

They also have reported that two sequence variants known to confer TP53 dysfunction—TP53 codon72 and MDM2 SNP309—coexinthen the majority of TP53 wild-type CPC (92%) and not in TP53-mutated CPC, which suggests a complementary mechanism of TP53 dysfunction in the absence of a TP53 mutation.

Antiviral effect was not affected by variants described to confer resistance.

In addition, most variants seem to confer very modest risks in the order of 1.2 1.6 fold, which are hard to detect given the statistical difficulties described above.

Several genetic polymorphisms have been described in TP53 gene [ 18] and some of these variants seem to confer different functions among the p53 [ 30- 32].

We were also able to show that the antiviral activity of Brazilian naturally occurring compounds was independent of HCV genotype and was not affected by variants described to confer resistance to Daclatasvir, a highly potent direct-acting antiviral drug targeting NS5A (Gao et al., 2010; Guedj et al., 2013; Lemm et al., 2010).

10 The ICEMR program thus has the opportunity to evaluate the impact of these and future interventions across endemic regions, which differ in the dominant Plasmodium species, mosquito vector species, resistance to antimalarial drugs, and human genetic variants thought to confer protection from infection and clinical manifestations of malaria.

The International Centers of Excellence for Malaria Research ICEMRR) has the opportunity to evaluate the impact of malaria control interventions across endemic regions that differ in the dominant Plasmodium species, mosquito vector species, resistance to antimalarial drugs and human genetic variants thought to confer protection from infection and clinical manifestations of plasmodia infection.