Sentence examples for variants the expression from inspiring English sources

When profiles were compared between tumors induced by each of the two transgenic Stat5 variants, the expression of a given gene was normalized to the median of the expression level in the wild-type mammary gland samples.

To ensure that the observed effects were based on protein expression of all TRAIL variants, the expression of the fusion proteins was confirmed by Western blot analysis using a mononoclonal mouse anti-GFP anbtibody.

Particularly, the influence of NRG1 risk variants on the expression of subunits of the NMDA receptor is unknown.

In addition, variants modulating the expression of a chromosome domain encompassing PLAG1 influence stature in cattle [ 39].

It has been reported that ABCG2 G34andnd C421A variants decrease the expression and the transporter activity of ABCG2 protein [ 14, 29– 31].

Finally, peptide-based vaccinations may induce the generation of tumour escape variants lacking the expression of a particular peptide epitope (Pawelec, 1999).

The presence of the M541L KIT variant, the expression of imatinib targets and cell cycle proteins on tissue microarrays (TMAs), as well as more classical clinical and biological factors were investigated.

In light of these findings, a more comprehensive genetic effort is warranted to identify the role of this and other rare TOR1A variants in the expression of late onset, focal dystonia.

We additionally show that these variants affect the expression of neuronal genes within or near the rearrangement.

We further performed a reporter gene activity assay to assess the potential regulatory function of these polymorphic variants on the expression of DLG4 gene.

[30] Further investigations on the effect of genetic variants on the expression levels and splicing isoforms in both T cells and B cells as well as intestinal epithelial cells will therefore be necessary.