Sentence examples for variants that result from inspiring English sources

Furthermore, alteration of miRNA expression in quiescent IBD tissues is consistent with the notion that genetic variants that result in differential gene expression (eg. that of regulatory molecules such as miRNAs) as well as mutations in the open reading frame are expected to contribute to multifaceted diseases.

Pipeline output is generated for variants that result in Δ Ri > ±1 bit.

The human Survivin gene locus has four known splice variants that result from alternative splicing of its messenger RNA.

They argued for a connection between greater ventral striatum reactivity and functional dopaminergic variants that result in decreased postsynaptic dopamine receptor density.

The identification of genes and genetic variants that result in disease, or contribute to disease susceptibility, is a critical objective in medical research.

However, RNA-Seq should be applied with caution, as it is possible to miss variants that result in the loss of a gene product.

Within the annotated Indels, there were 251 frameshift variants that resulted in feature elongation, and 262 frameshift variants that resulted in feature truncation (Additional file 1: Table S3).

Genetic variants that results in differences in disease phenotype are known as modifier genes [ 53].

The use of transient immune suppression and/or AAV capsid variants that results in reduced MHC-I presentation of AAV capsid-derived antigenic peptides may reduce this risk.

The detected products were determined to be HSPA8 mRNA splicing variants that resulted from skipping the second or simultaneously skipping both the third and fourth exons of the major mRNA isoform.

Out of these, only two were non-synonymous variants that resulted in amino acid substitutions in the predicted mature polypeptide chain of Adamts16 from Pro274 and Thr1170 in LEW rats to Ser274 and Ser1170 in S rats (Fig.  4).