Sentence examples for variants that reduce from inspiring English sources

Therefore, it is most likely that the texture memory in steel is caused by the preferential selection of those K S variants that reduce the interfacial energy between a precipitate and two adjoining parent phase grains at the same time, which we call the double K S relation.

Corpus-enrichment significantly mitigated the problem of missing phrasal variants that reduce recall.

The T1762/A1764 and A1896 mutations are the most common HBeAg-negative variants that reduce or abolish HBeAg production.

Therefore, we hypothesise that Ala946 is not causal itself but a marker for common haplotypes carrying functional variants that reduce IFIH1 transcription compared to other haplotypes with normal or higher expression.

Hence, the data are broadly consistent with a process whereby variants that reduce the ability to fight infections enter the population by mutation, but have been maintained at a low frequency by the action of natural selection.

Resequencing of ANGPTL4 uncovered both rare and common variants that reduce triglycerides and increase HDL (26).

This finding was supported by Bray and colleagues in Cardiff [ 29] who demonstrated that a schizophrenia risk haplotype tagged one or more cis acting variants that reduced expression of DTNBP1 in post mortem cerebral cortex mRNA of unaffected research subjects.

All exonic sequence variants, plus splice junction consensus sequence variants that reduced splice junction sequence similarity to the standard consensus sequences AG^GTRRGT (donor) or Y16NYAG^ (acceptor) (where ^ indicates the position of the splice junction), were reamplified from genomic DNA for confirmation of the presence of the variant.

Overall, these findings are in agreement with our findings regarding the BRCA1-3'UTR-variant, that reduced BRCA1 expression in the absence of germ-line protein coding sequence variants may be associated with aggressive tumor biology.

In Asians, the risk of irinotecan-induced severe toxicities is related in part to UGT1A1*6 (UGT, UDP glucuronosyltransferase) and UGT1A1*28, variant alleles that reduce the elimination of SN-38, the active metabolite of irinotecan.

We define inactivating variants as those that reduce the Ri of the affected binding site below 1.6 bits [20].