Sentence examples for variants that matter from inspiring English sources

The machine's algorithms examine these differences based on the investigator's search criteria, looking for medically relevant ones".You might filter down to the variants that matter for mutations known to be causative or associated with a disease," Mr. Conde of Knome said.

Developed long ago by animal breeding geneticists - we still heard references to the 'animal model' - such models gained a new lease of life in 2006 when plant breeders began to use kinships estimated from marker data: it is sharing of causal variants that matters, and pedigree can give only expected and not realized genome sharing.

If the p-value for the LRT is not statistically significant we conclude that the particular variant is the 'sole variant', i.e. it is the only variant that matters.

Variants that are identical can be assumed to be IBD; even if there is recurrent mutation and the identical variants are not IBD, it is only the identity of the variant that matters when directly testing a putative causal variant.

One intriguing finding in the study was that gene variants that raise a person's risk of disease may matter less than genes that protect against disease.

But the knockout can also hide variants that would otherwise matter, in which case the gene is called a potentiator rather than a capacitor [ 27, 28].

It does not matter what an "ideal" adaptive feature might be the only relevant factor is that variants that happen to result in greater survival and reproduction relative to alternative variants are passed on more frequently.

Try making variants that involve vehicles.

Concentrate on things that matter.

For Veridical, all that matters is that cryptic variants contain the word "cryptic" as part of their value in this column and that non-cryptic variants do not.

VAAST Yandell et al., 2011 is a step forward in both regards in that it uses an approach to variant classification that combines both amino acid substitution (AAS) information with variant frequency information, allowing it to score all variants no matter where they lie in the genome and with greater accuracy Yandell et al., 2011.