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Variants that include the age of publications are also irrelevant in our analyses, since the publications by the BuSs investigated are from the same publication years.
In addition to identifying splice variants that include or exclude polyglutamine-encoding exons, as in SCA6 [41] [42], [42], it will be important to identify any splice variants that alter physiological functions or protein-protein interactions of polyglutamine disease proteins, or that affect polyglutamine expansion-induced properties including protein misfolding and aggregation.
We report novel genome variants that include SNPs, indels and structural variations that enlarge the current repertoire of human genome variation.
The remaining 15,072 (11.4%) are structural variants that include 10,968 deletions, 2,600 insertions, and 1,504 complex rearrangements.
Only rs16890979 is associated with gout in Caucasians [ 7, 11], possibly because of linkage disequilibrium with the more strongly associated intronic variants that include rs6855911 and rs11942223 [ 7, 11].
The Lass5 gene transcribes two mRNA splice variants that include or exclude exon 9a and these two variants are termed Lass5 long and short transcripts respectively [13].
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This manuscript reports the results of an extensive study on the influence of molecular weight and architecture of a library of polylysine variants that includes linear, dendritic and hyperbranched polylysine.
The Ju 87 B-2s that followed had some improvements and were built in a number of variants that included ski-equipped versions (the B-1 also had this modification ), and at the other end, with a tropical operation kit called the Ju 87 B-2 trop.
Expression array experiments were performed using the Affymetrix Human Genome U133 Plus 2.0 Chip (Affymetrix, Santa Clara, CA, USA) that encodes 54,000 probe sets (with 47,000 transcripts and variants that includes 38,500 well-characterized genes) for integrative expression analyses of RNA mapping and histone acetylation, and for verification of the expression of novel transcripts.
Results from EST mining of 143 SNP-intron matches (a subset of the 170 variants that included INDELs) yielded 92 possible STEPs with EST sequences spanning the whole retained intron, as well as EST sequences matching a 40 base sequence spanning the spliced exon-exon junction (20 bases either side).
We downloaded the raw LD files for each population and searched for pairs of genetic variants that included dSNPs.
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