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Multinucleotide polymorphisms (MNPs), i.e. variants that consist of two or more adjacent SNPs, were filtered out if a stop-gain variant was found within the same codon as another SNP.
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The others were AS variants that consisted of novel combinations of known AS events.
We identified a bi-helix motif (residues 149 186) in the crystal structure of the catalytic core (CC) of the IN-Phe185Lys variant that consists of the α4 and α5 helices connected by a 3 to 5-residue turn.
Compared to the reference, we identified 460 mtDNA variants that consisted of 414 single nucleotide substitutions, 410 homoplasmic and 4 heteroplasmic variants (Table 1).
NK1 is an alternative spliced variant of HGF/SF that consists of the N-terminal (N) and first kringle (K1) domains and has partial agonistic activity.
The output of variants was stored in the variant call format (vcf) that consisted of meta-information for individual variant with respect to reference sequence in the form of various parameters.
The total number of variants found for each library (Table 1) was subjected to a filter that consisted of choosing variants that had a total number of reads 50% greater than the number of total reads of their reference miRNA previously reported, so that low-abundance and probable non-functional variants were discarded.
For a given D-value threshold, we determine a detection region that consists of all variants within a specified radius of any variant above the threshold (10 kb for the results presented here; see Figure 2 for an illustration).
Two types of multisensors were produced that consisted of four AChE variants each.
Therefore, detection of a population that consists of a complex of heterogeneous variants is necessary in the diagnosis of FCoV infection.
Similar to a configuration model with a few configurations produce several variants of software systems in [2, 3], a feature model that consists of few features can produce several numbers of configurations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com