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In the test group, about 80% of genes possessed variants that affected gene expression, and several hundred of the affected genes were imbalanced toward the father's genetic contributions... keep reading.
A similar study of clinal adaptation in Drosophila melanogaster also found a considerable contribution of copy number variation to population differentiation, including large variants that affected multiple genes [17].
We further investigated the variants that affected CDSs, and compared them to reported virulence determinants.
For the gene-level analyses, variants that affected multiple genes were included as variants in each gene.
For the individual-level analyses, the most severe consequence was selected for variants that affected multiple genes based on the functional impact class supplied by CAVA.
Similar to previous findings in dairy cattle [ 32], the bivariate analysis detected more associations than the univariate analysis, including genetic variants that affected the same trait expressed in each of the laying periods and genetic variants that affected only expression of a trait in one of the laying periods.
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The study was designed to identify genetic variants that affect the risk of developing hormonally mediated (ie breast, ovarian and prostate) cancers.
The scientists used a database of more than 100,000 Icelanders to see how dozens of gene variants that affect educational attainment appeared in the population over time.
Furthermore, variants that affect chromatin at distal regulatory sites frequently also direct changes in chromatin and gene expression at associated promoters.
Thus, neurogenetics includes the study of the behavioral consequences of gene variants that affect nervous system development and/or function.
They will also map trans-acting genetic variants that affect TF activity (coined 'aQTLs' by one of the investigators) in each tissue.
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