The study was designed to identify genetic variants that affect the risk of developing hormonally mediated (ie breast, ovarian and prostate) cancers.
In mothers and children with gene variants that affect folate metabolism, not taking prenatal vitamins before conception was associated with an up to sevenfold increase in the risk of autism, the researchers found.
Thus, neurogenetics includes the study of the behavioral consequences of gene variants that affect nervous system development and/or function.
We explore in this paper the role of genetic variants that affect cell size and proliferation in the determination of organ size.
Expression quantitative trait loci (eQTL) mapping studies have become a widely used tool for identifying genetic variants that affect gene regulation.
This week, a group in Iceland suggests individualizing healthy and high levels for each man tested by focusing on genetic variants that affect PSA levels.
In the case of modularity, it means that among gene variants that affect different numbers of traits, those gene variants are selected which affect lower numbers of traits, as well as certain combinations of traits.
We searched for variants that affect disease risk in a large, multigenerational family with history of HSCR in a linkage region previously associated with the disease (4q31.3 q32.3) and exome wide.
"We found a whole range of genetic variants that affect the impact of other variants," says Thompson, "and we are beginning to understand the guiding principles of these gene networks".
Failure of complementation in QCTs revealed that invected, mastermind, cricklet and CG14591 have natural allelic variants that affect DT.
Advances in technology and affordability are rapidly allowing GWAS to identify genetic variants that affect risk for human disease (http://genome.gov/26525384).gov/26525384
