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In the rodent, the short variants show higher expression in adult brains whereas long variants dominate during embryonic stages in rat [47].
Specifically, smooth transparent M. avium variants show higher motility on hydrophilic surfaces and increased GPL production; conversely, rough variants show diminished motility and impaired GPL production [ 22].
Mendelian disease variants, recurrent cancer somatic mutations, and complex disease variants show higher enrichment within transcription insulator regions than cancer predisposing germline variants.
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The two datasets also represent the extremes of the concordance identified in variant annotation, with CDS variants showing high (>90%) concordance in all conditions while 'other' variants show high discordance (up to 56%).
The three crystallized cpOYE variants show high overall structural similarities with the parental OYE1, yet exhibit significant conformational perturbation near the old and new termini regions.
Interestingly, the Lys114Tyr, Lys114Val, Lys114Met and Lys114Ile variants showed higher catalytic efficiencies when compared with the wild-type protein.
Comparison of CMVarI and CMVarII G, E variants showed higher GFP and E1 for CMVarI G, E variants.
No specific allelic variants showed higher activities for every procarcinogen tested.
Interestingly, samples with both PTEN mutations and SDHx variants showed higher ROS compared with samples with SDHx variants alone.
However, the cultures of both amoeba variants showed higher growth in BI-S-33, in which the iron source is primarily ferric citrate, not in B-holo-Lf and 1(b)).
We found that the E,E SS) S32 variants showed high fluorescence intensity at the equilibration phase of the DSF experiments (Fig. 1D), suggesting that they were partially unfolded at ambient temperature.
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