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All three variants share the same underlying pathology.
Two pairs of variants share the same 5' exon but differ in the 3' exons.
Conceptual translation indicates that the two SRF1 variants share the ECD and the TM but differ in their intracellular domains.
Splice variants grouped according to PDE4 gene isoform type and not splice variant form (Additional File 3), because all isoform splice variants share the same exon pool (i.e. catalytic domain exons).
The two transcript variants share the same four 5′ exons and the exon 5 of the shorter variant is actually located in the intron 4 of the long transcript.
Development of the AKAP7β exon occurred in mammals (opossum), and while AKAP7β and α splice variants share the same amino terminus, the AKAP7β-specific exon confers a cellular localization distinct from the AKAP7α splice variant [ 46].
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According to their crystallography, twin twin interactions are classified into Type I for two twin variants sharing the same ⟨11¯20⟩ zone axis and Type II for two twins with different zone axes.
Taking advantage of the high sequence designability of IDPs, we have produced an array of PNT variants sharing the same hydrophobicity, but differing in net charges per residue and isoelectric points (pI).
In the majority of the HAART-treated patients, the estimated tMRCA of the tree root (which represents the time at which the sampled viral variants shared the same ancestor) [39], was within 12 months before treatment initiation, whereas it was placed years before T0 in both of the group C controls.
We define here pairs of variants sharing the same pattern of splicing sites and exon/intron organization as "iso-structural orthologous splicing variants" or more briefly "iso-orthologs".
This allows the determination of the expression of ORF1, as well as the ORF1a and ORF1b variants (sharing the N-terminal epitope).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com