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In this work we aim to take a step ahead in the development of the discipline by introducing a large amount of BFOA variants resulting from the combination of some advanced design decisions applied on Dasgupta et al.'s self-adaptive version.
Functional analysis of Pol ι variants resulting from deletion and point mutations representing polymorphic POLI alleles is required to better understand the role of this Pol.
Species-specific neuropeptide prohormone variants resulting from duplication have been reported in other mammalian species.
More than 260,000 protein variants resulting from alternative splicing have been annotated to date [ 3].
We took various precautions to eliminate sequence variants resulting from mistakes in reverse transcription or PCR.
We are not suggesting that Veridical be used to analyze all variants, resulting from exome or whole-genome sequencing experiments.
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Column "×" shows that the number of inactive variants resulted from amino acid substitutions.
Transcript variants result from alternative promoters usage and encode for the same KLK6 protein, since all mRNA sequence changes occur at the 5′-untranslated region, while splice variants result mainly by skipping coding exons and they either encode for small proteins with low identity to KLK6 or to no proteins at all [6, 7].
Analysis of EBV genomic sequences indicated that the majority of EBV miRNA nucleotide variants resulted from post-transcriptional modifications.
An example is given in Figure 3, demonstrating sequenced isomiRs for miR-1, which indicated that the majority of porcine miRNA nucleotide variants resulted from post-transcriptional modifications.
It is possible that the altered catalytic activities of the PEGylated variants resulted from subtle structural perturbations to the enzyme's 3-dimensional fold.
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