Sentence examples for variants resistant to from inspiring English sources

In this report, the TaqMAMA method was adapted for the detection and quantitation of minor HCV variants resistant to the protease inhibitor boceprevir (SCH 503034) from clinical samples.

HIV-1 variants resistant to small molecule CCR5 inhibitors such as vicriviroc (VVC) have modified Env complexes that can use both the inhibitor-bound and -free forms of the CCR5 co-receptor to enter target cells.

This results from selection of naturally-occurring variants resistant to the drugs used.

Vertical transmission of HIV-1 variants resistant to reverse transcriptase inhibitors has been reported and some studies suggest that resistant mutations are selectively transmitted [3] [5].

During the last two decades, the incidence of malaria has been increasing, largely due to an emergence of parasite variants resistant to the two most widely used drugs, chloroquine and sulphadoxine/pyrimethamine.

This is further supported by the fact that the ciliary localization of Gli2 variants resistant to proteolytic processing is also efficiently inhibited by forskolin treatment (Fig. 4C, see below).

JURKATR is a JURKAT variant resistant to CD95-mediated apoptosis obtained after continuous exposure to agonistic Apo-1 antibody [ 37].

Even considering these data, the report of an HBV variant resistant to adefovir [ 5] adds weight to the need for developing new therapies to treat CHB.

However, the efficacy of this immunoRNase could be further improved for a more efficient killing, as required for a successful cancer therapy, by replacing the native human RNase with a more cytotoxic variant resistant to the RI.

Furthermore, these variants are resistant to the RNAi, potentially by stoichiometrically overwhelming this cellular mechanism.

Together, our data demonstrate that hinge domain null AR splicing variants are resistant to SPOP-mediated degradation.