Sentence examples for variants rendering the from inspiring English sources

Despite the tremendous recent progress in this field, current efforts toward the directed evolution of these hybrid biocatalysts mainly rely on the laborious, individual purification of protein variants rendering the throughput, and hence the outcome of these campaigns feeble.

Thus, there is the possibility that the tools will introduce significant genomic alterations besides the desired DNA variants, rendering the resulting cell lines not truly isogenic and introducing a source of confounding.

Consistent with the results of previous studies (15, 16, 19, 25), GFP-tagged FUS variants rendered cytoplasmic by the introduction of mutations or truncations abrogating nuclear import were diffusely distributed in the cytoplasm of SH-SY5Y neuroblastoma cells or primary hippocampal neurons (Fig.  1A, Supplementary Material, Fig. S1A).

In particular, a small number of patients with cellular and collapsing variants rendered statistical analysis unavailable.

Some sheep carry genetic variants that render the normal prion protein resistant to conversion into the abnormal form that causes scrapie.

The vulnerability cancelation errors in the higher-order variants can render the whole schemes useless.

Identifying the subset of variants that renders the smallest p-value by testing subsets exhaustively, however, is computationally demanding.

For example, when a non-trivial gene structure, perhaps with newly uncovered transcript variants, has rendered the established probe set structure obsolete.

If for a given drug-gene pair, there are inconsistencies in the published data (for the gene or specific variants) that render the data inconclusive, the CPMC may still choose to include these in the PhAESIS report, and to seek guidance from the PAG on the validity of the data.

We hypothesized that the low NA activity possessed by the R292K variant might render the mutant strain less competent at competing with the wild-type virus.

The low allergenicity and high immunogenic activity of Art v 1 variant C49S renders the molecule an attractive candidate for hypoallergen-based immunotherapy of Artemisia pollen allergy.