Sentence examples for variants relevant for from inspiring English sources
Alternatively, unexplored epistatic interactions with other gene variants relevant for the TLR-mediated responses (e.g. TLR4 Asp299Gly, TIRAP/Mal Ser180Leu, etc) might be needed to be able to detect Ser602Ile effects on this devastating clinical condition.
In summary, our results require replication but build upon our previous report of potential host genetic variants relevant for HPV persistence and those relevant for progression to CIN3/cancer.
To identify variants relevant for longevity, analysis on the genomes of many more of such individuals must be performed.
Unfortunately, classical candidate gene studies have proven largely unsuccessful in reliably detecting novel genetic variants relevant for obesity.
Many current methods for the detection of gene variants relevant for inherited disorders like malignant hyperthermia (MH) rely on the polymerase chain reaction (PCR).
A polygenic basis of obesity implies that the specific set of polygenic variants relevant for obesity in one individual is unlikely to be the same in another obese subject.
While these modifiers may not address all human phenotypes, they comprise a five-tier system of classification for variants relevant to Mendelian disease as addressed in this guidance.
Given that the Xpr1 ECL3 receptor variants are relevant for infectivity of different MLV strains [ 40, 57, 59], we were interested in assessing possible viral variants associated with animals carrying alternative alleles at the N503K substitution in XPR1 (haplotype I/II versus haplotype III).
The availability of a rapid and inexpensive method for the identification of MUTYH sequence variants is relevant for the diagnosis of colorectal cancer susceptibility, since the MAP phenotype is highly variable.
By genotyping a large number of SNPs, there is a good chance that at least one SNP will be in LD with common functional variant(s) relevant for the investigated phenotype.
Moreover, there have also been reports that the association of 5-HTTLPR may only be present when paired with an intron-2 (STin2) polymorphism [ 11] and that the intron-2 (STin2) polymorphism itself may be the variant more relevant for ADHD.
