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To assemble the MgPa operon using fragments containing multiple variants, only the most predominant sequence was selected.
From the recently identified T2D risk variants only the risk variant of the FTO gene (rs8050136) showed statistically significant association with BMI, FMI, and WC.
For splice-site variants, only the genotype is listed.
For each group of predicted splice variants, only the longest gene was taken as gene representative.
If a given gene had multiple alternative splicing variants, only the one with the longest coding sequence was used.
When two exons overlap (which occurs in the case of splice variants), only the longest exon is considered.
Similar(43)
The annotation was standard in discovery mode, emitting variants only, using the GLM model for SNP + INDEL.
Direct sequencing was used to confirm the integrity of the constructions and to verify that the variants only differed in the number of CA-repeats.
ClinSeK identifies variants only at the targeted sites and does not discover any novel variant.
Autoradiography upon Se labeling of all cellular selenoproteins confirmed that Sec incorporation into the TrxR1 variants only occurred in the Txnrd1 fl/fl and Txnrd1 498Sec MEFs.
Interestingly, there were also about 3,400 variants only identified by the combined reference strategy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com