Sentence examples for variants needs to be from inspiring English sources

However, the pathological role of these variants needs to be determined by functional studies.

These findings require replication in large samples and the role of these variants needs to be clarified by functional studies.

Each of the underlying variants needs to be scrutinized with regard to possible annotation errors and to be confirmed by Sanger sequencing.

Due to the extensive non-independence between SNPs and the limited haplotype diversity within regions of strong LD (LD blocks) in the human genome, only a subset of selected SNPs, instead of all variants, needs to be analyzed to capture the majority of common genetic variation within such blocks.

Each of the putative stop codon introducing variants needs to be scrutinized by manual examination of the reads, the re-annotation of the affected genes and Sanger sequencing.

However, because of the relatively small effect size of the two SNV in PPARA and POR*28, the clinical applicability of the genetic testing of these sequence variants needs to be further investigated in even larger cohorts.

For these configurable products the support of all variants need to be addressed both by the design phase and the production phase.

Or equivalently, how many more variants need to be found in order to explain the entire heritability?

However, clinical cut-off levels for those minority variants need to be defined.

Bona fide stop codon causing variants need to be typed in a representative sample.

Genes with frequent rare variants need to be appropriately ranked in order to reduce false associations and streamline clinical analysis.