Sentence examples for variants might affect from inspiring English sources

However, in principle strong non-additive effects between variants might affect the risk estimates, and thus care has to be taken when interpreting the results.

This suggests that these 108 variants might affect gene expression in OMA.

A number of genetic variants might affect several genes influencing vulnerability to eating disorders.

Evidence from GWAS (Table  1) supports the notion that common variants might affect HbA1c levels through their effects on glucose levels and also through erythrocyte biology.

Therefore, the T310K mutation, prominent in cervical cancer variants, might affect the three-dimensional structure of this helix and hence its ability to bind to DNA.

Thus, expression of these variants might affect AD risk by altering the physiological role of SORL1 in the processing of APP holoprotein (Schmidt et al., 2012).

The p.Arg830Trp variant might affect AHI1 complex stability/formation (Louie et al., 2010).

It has been also suggested that the BRCA2 N372H variant might affect fetal survival in a sex-dependent manner.

In the light of the few reports of EB causing mutations in livestock we hypothesized that a causative variant might affect one of the known EB candidate genes.

The authors suggested that the reduced protein levels and altered ATPase activity of the BCRP C421A variant might affect the oral absorption and/or elimination pathways of gefitinib thereby increasing the steady-state gefitinib plasma concentrations leading to the diarrhoea.

The human amino acid position orthologous to chicken site 5 is conserved (F10) and is located in the signal peptide of the protein, indicating that the L5 chicken variant might affect activation of the receptor protein.