Sentence examples for variants may render from inspiring English sources

The results suggest that CXCR1 variants may render individuals UTI-prone by lowering CXCR1 expression and by incapacitating the neutrophil-dependent host defense against UTI.

Furthermore, the identification of additional genetic variants – both protective and risk variants – may render it possible to use patterns of predisposition to tailor individual management of these conditions.

We speculate that the reduced enzyme activity conferred by the SULT1A1 variant alleles may render the pancreatic cells more susceptible to some unknown xenobiotics or hormones since neither smoking nor dietary mutagen exposure showed interaction with this genotype in modifying the risk of PC.

For antagonistic SNPs, on the other hand, we describe plausible mechanisms that may render variants protective against one trait and predisposing to another, labeling the affected genes/loci as pleiotropic.

Through population studies, we have learned that certain CYP1A1 variants, such as Mspl polymorphism, may render the carriers more susceptible to cigarette-induced lung cancer or severe coronary atherosclerosis.

Furthermore, the identification of additional genetic variants, both protective and those increasing risk, may render it possible to use patterns of predisposition to tailor individual management of these conditions.

In some cancer cells, let-7 downregulation may render the long 3′UTR variants accessible to other miRNAs or RNA binding proteins that affect mRNA stability and thus may lead to a switch in the variant's downregulation (Selbach et al, 2008).

In practice, the chaotic systems are inevitably subject to some environmental changes, which may render their parameters to be variant.

The enormous complexity of the auditory system suggests elaborate gene interactions may render it vulnerable to accumulation of deleterious variants otherwise tolerable in the context of a neutral genetic environment.

Therefore, the changes in cytokine production in CD4+ T cells elicited by GSK3 inhibition may also suggest a mechanism whereby dysregulation of GSK3 may render an individual susceptible to autoimmune disease; in fact, a particular allelic variant of GSK3β is a susceptibility factor for multiple sclerosis 52.

That may render them politically unrealistic.