Sentence examples for variants may play from inspiring English sources

Genomic variants may play an important functional role in the human transcriptome regulation in both normal and disease states.

Alternatively, the short Ugt RNA variants may play some roles in the regulation of the Ugt gene expression and never encode any polypeptide.

Taken together, these findings indicate that expression and signaling delivered by specific splice variants may play a critical role in regulating autoimmune disease and illustrates the importance of carefully dissecting gene expression data.

On the one hand, previous papers showed that intron variants may play important roles in gene expression [44], mRNA secondary structure formation [45], and transcriptional suppression of the genes [46].

The important finding of this study is the identification of a genetic basis for DNA methylation susceptibility; it indicates that genetic variants may play an indirect role in increasing the risk of MSI-H colorectal cancer.

Other factors than these genetic variants may play more important roles in CCA risk and survival.

Given that the Ser9Gly variant may play a putative role in the DRD3 function, further studies on the DRD3 are warranted.

Regarding the results obtained for the sHFE protein variant, although its function still requires further investigation, we propose that this variant may play a role in systemic iron metabolism regulation.

This variant has been shown to associate with the metabolite acylcarnitine 9 in a GWA study of 163 metabolic traits measured in human blood (initial step: n = 1,809/replication step: n = 422), indicating that this variant may play a role in human lipid metabolism [38].

This study suggests that the VDR genetic variant may play a role in susceptibility to lead accumulation.

Such screening is especially valuable if the variant may play a functional role in the protein or in gene expression.