Sentence examples for variants may increase from inspiring English sources

These variants may increase susceptibility to bladder cancer through complex gene-gene and gene-smoking interactions [ 12].

This study demonstrates that certain combinations of gene variants may increase susceptibility to SLE, suggesting this approach for future studies.

Research in an expanded study population now provides additional evidence that exposure to insecticides, paired with specific metabolism gene variants, may increase the risk of childhood brain tumors [ EHP 118 144 149; Searles Nielsen et al.].

The study's key implications are twofold: first, that children with variant iron-metabolizing genes may be especially susceptible to the effects of lead at low exposure levels, and second, that genetic variants may increase risk at one life stage and decrease it at others.

The association between the amount of mtDNA and a variant in a regulatory region of the mitochondrial genome can be interpreted in two ways: the frequency of the variant may increase as a consequence of increased turnover of mtDNA, or it may itself affect the replication of the mtDNA molecule.

Thus, this promoter variant may increase the risk for SD by influencing RGS17 transcription.

The F variant may increase susceptibility to elastase-induced lung damage but not emphysema, whereas co-inheritance with the Z deficiency allele may predispose to emphysema despite reasonable plasma concentrations of alpha-1-antitrypsin.

Recent meta-analysis performed by Hu et al., which covered 5509 breast cancer cases and 6542 controls from 6 case control studies, has not revealed any association among the whites and has suggested that the polymorphic variant may increase the risk only among Africans [ 42].

For example, the ClinSeq consent document [ 21] contains specific language about the availability of genetic counselors to participants who may experience psychological problems as a result of knowing that they carry genetic variants that may increase their risk of disease.

These recent studies illustrate the power of GWA studies in large sample sizes to identify gene variants that may increase risk of breast cancer, although these are not high-penetrance genes.

But the same variant also may increase the form of folate that can be used to make thymidine, one of the bases in DNA, and to prevent mutagenic uracil from being incorporated instead.