Sentence examples for variants may alter from inspiring English sources

APOE (chromosome 19q12-13.2) is known to have a key role in determining inter-individual differences in lipid metabolism [5], [6], and APOE gene variants may alter glucose metabolism [6], [7] moderated by obesity [8] [10].

These natural variants may alter the function of the protein.

59, 66, 67 Conversely, genetic variants may alter the effectiveness of a medication.

These variants may alter the progestin responsiveness of a tissue and contribute to the abnormal growth associated with breast cancer.

Through a series of bioinformatic and literature investigations, we have been able to infer how these SNP variants may alter paclitaxel response.

It was also reported that PON1 genetic variants may alter the risk of epithelial ovarian cancer among smokers and obese women.

These results suggest that the OriB variant may alter protein binding in the NCR and thereby affect mtDNA replication.

For the remaining protein-coding genes with intronic SNP variants: ROBO1, LPHN2 and PTPRD, it remains unclear how their variant may alter their gene product.

Two bioinformatics tools, Sorting Intolerant From Tolerant (SIFT) [ 40] and Polymorphism Phenotyping (PolyPhen) [ 41] indicate that this variant may alter the function of the protein.

By abolishing the expression of Darc on erythrocytes, the Duffy null variant may alter the concentration and distribution of chemokines in the blood (27).

Thus, it is tempting to speculate that EGFR variant may alter binding of its specific ligands leading to a particular phenotype of EGFR signaling.