Sentence examples for variants localized in from inspiring English sources
With the exception of AtPP5 that has been shown to contain two splice variants localized in the cytoplasm/nucleus and ER, respectively [16], the splice variants of all other genes remain to be verified experimentally.
Putative impact of variants has been evaluated, focusing on non-synonymous variants localized in the coding sequence (CDS).
We found six different sequence variants localized in intronic regions of EGFR, two of them previously described in Ensembl [ 17].
Moreover, most eukaryotic organisms have several HSP70 variants localized in all major subcompartments, the cytosol, the nucleus, ER, mitochondria, and also chloroplasts [ 74, 77].
Furthermore, SSPPs analysis proved to be very valuable and reliable in predicting aberrant splicing for variants localized in the intronic 5′ and 3′ splice-site region, whereas it was neither conclusive nor always successful in the prediction of the consequences of such loss.
As the RhCC variant localized in rhabdomeres, it implies that the eye phenotype was not due to a dramatic alteration in rhodopsin trafficking.
The NLGN3 gene is composed of eight exons with the start codon in exon2[ 40] and the SNP rs4844285 implicated was an intronic common variant localizing in the intron 2 of the NLGN3 gene with unknown function.
EGFP-fused MUTYH variants localized mainly in the nuclei and were not distributed as widely throughout the cell as EGFP alone.
We further examined 22 variants found in RAS family genes and 135 variants localized to exons encoding the kinase domain of respective proteins.
In subjects S1, S2 and S3 a well-supported subclade of R5-using viral variants was localized in PBMCs and distinct from quasispecies in contemporaneous tissues where X4 and R5 variants commingled (Fig. 1a, 1b, and 1c).
In this work, we described 19 novel variants localized along the entire coding sequence (eight missense, two frameshift, three nonsense, five splicing mutations, and one small deletion).
