Sentence examples for variants lacking an from inspiring English sources

To determine if viral infection could uniquely affect the expression of PML splice variants lacking an NLS, total RNA was harvested from uninfected and HSV-1 (F -infected human primary F -infected (MRC5) and analyzed by Reverse Transcriptase Polymerase ChumanReaction (RT-primary

Furthermore, some AR variants lacking a ligand-binding domain have been detected in both normal and cancerous tissues [ 22- 24].

Natural LPS variants lacking a single acyl chain engage less well with TLR4, yet can cause clinical disease and so may be better placed to evade the innate immune system [ 123].

Because a completely undigested product arising from incomplete activity of the restriction enzyme cannot otherwise be distinguished from the (DEFA3) variant lacking an internal HaeIII site, it was necessary to introduce this artificial site into all products to act as a check of complete digestion by HaeIII.

Two S. scrofa non-coding HSFY variants lack a SINE, but also do not cluster with the short form copies (OTTSUSG00000005614 and 5682; orange in Fig.  3).

These splice variants lack a 41-amino-acid sequence encompassing the C-terminal part of IgFLNa19 and the N-terminal part of IgFLNa20, including the first strand of IgFLNa20.

Rats expressing an AHR splice-variant lacking a portion of the transactivation domain are highly resistant to dioxin-induced toxicities.

In contrast, both L-FU and a variant lacking a full kinase domain (2HFU) were able to enhance GLI2 induced transcription.

The only marked differences in the superimposition of these two sets of resonances occurred at residue 89, for which the G89P variant lacked an amide resonance, and Ile for which the N of the G89P was shifted downfield as anticipated from the inductive effects resulting from the side chain substitution for the preceding residue [ 42, 43].

Finally, peptide-based vaccinations may induce the generation of tumour escape variants lacking the expression of a particular peptide epitope (Pawelec, 1999).

Given these results, it is difficult to speculate on the structure of the isoform lacking the 5th TMD, and how splice variants lacking exon 6 might exhibit a dominant negative effect via interaction with wild-type DAT.