Sentence examples for variants is largely from inspiring English sources

By contrast, the pathological relevance of the known SPINK1 promoter variants is largely unknown.

This increase in observed variants is largely the result of rare variants assayed by whole-genome sequencing (WGS).

Genome-wide association studies have implicated numerous candidate genes for inflammatory bowel disease (IBD), but evidence of causality for specific variants is largely absent.

As summarized in Table 4 (right columns), a correlation indeed exists between changes in enzymatic activity caused by amino acid substitutions and the relative yield of 4c Co II)rrinoid, indicating that the reduced activity of the variants is largely due to perturbations to the Co II)/Co(I) reduction step.

While these data illustrate that the weight differences observed for all of the variants are largely related to increased adiposity, for some loci fairly large proportions of the weight difference between homozygotes is attributable to lean mass.

However, protective CCR5 variants are largely absent in African populations, in which sporadic resistance to HIV-1 infection is still unexplained.

Our East Asian GWAS meta-analysis has identified novel variants associated with HbA1c as well as demonstrated that the effects of known variants are largely transferable across ethnic groups.

By contrast, CPY*-D1 and CPY*-D2 variants were largely absent in the budded vesicle fraction (Figure 3A).

However, the timing of the onset of HLA-A2-restricted responses, their impact on viral evolution, and the potential efficiency of subsequent CTL responses generated towards autologous epitope variants are largely unknown.

Results from functional analyses of variants are largely supported by sequence alignment and protein modelling predictions.

Adenylated DNA adapters incubated overnight with the multiply mutated T4 Rnl2tr variants were largely unchanged.