Exact(3)
In the INMA-Sabadell cohort we analyzed whether child genetic variants interacted with LC-PUFA levels in colostrum to influence cognition.
Furthermore the cell lines that stably expressed Smac56-V5, Smand0-V5, and Smacδ-V5 were transiently transfected with GST-XIAP to determine whether the cytosolic Smac variants interacted with XIAP.
The effects would be strong if the variants interacted with each other, which, however, may not be the case with the type 2 diabetes genes detected.
Similar(57)
Complex diseases may result from many genetic variants interacting with each other.
We hypothesize that aging and longevity, as complex traits having a significant genetic component, are likely to be controlled by nuclear gene variants interacting with both inherited and somatic mtDNA variability.
Identifying the specific genetic variants interacting with TZDs and resulting in edema or cardiovascular events may have important clinical consequences and enable genetic variant directed use of TZD drugs among people with dysglycemia.
This model originated from the hypothesis that schizophrenia results from the cumulative impact of multiple common small-effect, genetic variants interacting with environmental exposures to exceed a biological threshold [ 62].
Env variants interacting with CD4/CXCR4 (rather than those having a preference for CD4/CCR5) are mostly encoded by syncytium-inducing HIV-1 strains, and a strong correlation between CD4+ T-cell decline and infection by syncytium-inducing HIV-1 variants has been established.
It was found that a partial dislocation ([0¯110]) in moving the ε variant interacted with a partial dislocation ([10¯10]) in the stationary ε variant, and this interaction resulted in the formation of a stair-rod dislocation ([2¯1¯10]) which connects two ε variants.
In our previous study, some, but not all genetic variants interacted significantly with biliary stone status to effect biliary cancer risk (Hsing, 2008).
We further explored the way two variants interact with interaction plots.
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