Sentence examples for variants indicating a from inspiring English sources

A72P also disrupts dimerization of nonfunctional variants, indicating a common structural basis for dimerization.

The Km(Trp) values for TPH2A and TPH2B were nearly similar (Table 2), but significantly higher for the edited variants, indicating a reduced affinity for the substrate Trp (Table 2).

Treating the gastric cancer cell lines with a methyltransferase inhibitor restored expression of the RASSF2A variants, indicating a role for DNA methylation in the silencing of RASSF2A expression.

Approximately 35% of Europeans and 52% of Chinese people are known to carry at least one of these variants, but no individual was noted to have all three variants, indicating an embryonic lethal combination.

We found a consistent (and significant) protective effect for these variants indicating an independent association with toxic maculopathy (Table  3).> -wrap-foot> *Adjointlyjointly for age, gender, treatment duration and daily dose per ideal bodyweight.

Finding no previously identified variants indicates a novel variant in the proband analysed.

A high sequence similarity between the inactive ClpR and the active ClpP variants indicates a common ancestor [ 40].

Structural analyses of the three TaEXPB11-Chinese Spring variants indicate a localised gene duplication producing non-coding gene copies.

This allelle confers a threefold increased risk of fibrosis progression over carriers of the T399I variant, indicating a protective role in fibrosis progression of the c.1196C→T (rs4986791) variant at this location (p.T399I), along with another highly co-segregated SNP, c.896A→G (rs4986790), located at coding position 299 (p.D299G).

FISH for AChE-R protein variant indicated a significant increase in the number of stained cells in the MG-thymomic section compared to healthy thymus (Figure 5A).

All other detected mutations are missense variants, indicating that a complete loss of ECHS1 function may be embryonic lethal.