Sentence examples for variants in populations from inspiring English sources
We discuss the advantages and drawbacks of the two approaches and the implications of mapping regulatory variants in populations with greater genetic diversity.
The results therefore strongly suggest that FTO and MC4R might be the only two major-effect genes for obesity with common variants in populations of European ancestry.
As IBS has been traditionally used in genetics studies to identify variants in populations, it is thus novel to apply the idea in cancer samples, especially in this particular context of assessing matched normal-tumor pairs.
While our theoretical model of the evolution of alternative splicing is purely deterministic, genetic drift could also be involved in the segregation of splicing variants in populations, like any other molecular marker [56].
Our evolutionary model will however allow us to state the conditions for the maintenance of existing splicing variants in populations, and therefore the maintenance of alternative splicing per se.
This may reflect differences in linkage disequilibrium (LD) between the genetic variants in populations of European and African ancestry [17], as well as the effects of other as yet uncharacterized gene-gene or gene-environment interactions that may be distinctive for each racial group.
And γ j = 2 N r e f s i is the scaled selection, in which s i is the relative selective advantage of variants in population i.
Estimating the burden of disease, including relative risks of incident disease, associated with genetic variants in population-based settings.
Their frequencies varied from 10.54% and 10.44% (the most abundant variants in population A and B, resp).
To address this issue, we have developed CNVassoc, an R package for carrying out association analysis of common copy number variants in population-based studies.
The CDCV model of schizophrenia suggests that relative common (often > 5%) genetic variants in population might confer minor or modest risk (i.e., OR = 1.1-1.5 1.1-1.5
