Sentence examples for variants in population from inspiring English sources

And γ j = 2 N r e f s i is the scaled selection, in which s i is the relative selective advantage of variants in population i.

Their frequencies varied from 10.54% and 10.44% (the most abundant variants in population A and B, resp).

The CDCV model of schizophrenia suggests that relative common (often > 5%) genetic variants in population might confer minor or modest risk (i.e., OR = 1.1-1.5 1.1-1.5

down to 0.013% and 0.014% (the least abundant variants in population A and B, resp .. 186 haplotypes were common to both populations and their frequencies were all above 0.02%.

THE idea of using identity-by-descent (IBD) haplotype sharing to detect signals of disease-causing variants in population samples is not new (Houwen et al. 1994; Te Meerman et al. 1995); however, the greatly increased density of SNP markers now makes it possible to detect much smaller segments of IBD.

The results therefore strongly suggest that FTO and MC4R might be the only two major-effect genes for obesity with common variants in populations of European ancestry.

We discuss the advantages and drawbacks of the two approaches and the implications of mapping regulatory variants in populations with greater genetic diversity.

As IBS has been traditionally used in genetics studies to identify variants in populations, it is thus novel to apply the idea in cancer samples, especially in this particular context of assessing matched normal-tumor pairs.

While our theoretical model of the evolution of alternative splicing is purely deterministic, genetic drift could also be involved in the segregation of splicing variants in populations, like any other molecular marker [56].

Our evolutionary model will however allow us to state the conditions for the maintenance of existing splicing variants in populations, and therefore the maintenance of alternative splicing per se.

Estimating the burden of disease, including relative risks of incident disease, associated with genetic variants in population-based settings.