Sentence examples for variants in cellular from inspiring English sources

Kozyra, M., Ingelman-Sundberg, M. & Lauschke, V. M. Rare genetic variants in cellular transporters, metabolic enzymes, and nuclear receptors can be important determinants of interindividual differences in drug response.

The differential expression of genes mediating carbohydrate metabolism indicates involvement of the STAT5 variants in cellular homeostasis as well.

Molecular analysis highlighted that, although A2-ELA is more stable than A2-EAA, T cells can distinguish between these variants in cellular assays [ 19].

Delobel et al. suggested that the emergence of X4 variants on HAART may be due to the preferential implication of X4 variants in cellular reservoirs, either through a progressive replenishment of the pool of resting memory CD4+ T cells by cells derived from long-lived naive CD4+ T cells harboring archival X4 species, or through the preferential residual replication of X4 viruses on HAART.

In this aspect, it is necessary to perform further studies to verify the in vivo impact of those functional pol ι variants in both cellular and organismal contexts.

In fact, the different roles of the OPN splice variants in angiogenesis, cellular invasion, cancer progression, and metastasis are widely discussed in the literature [ 14, 17, 18, 21, 27].

The existence of nesprin variants in sub-cellular compartments other than the NE was first observed when antibodies were generated to different domains of nesprin-1 and nesprin-2.

Recently, FSGS has been classified in five subcategories: collapsing variant, tip lesion variant, cellular variant, perihilar variant, and FSGS not otherwise specified (NOS) [ 20, 22 for further reading].

This conservation underlines the importance of this splice variant in multiple cellular functions.

One is an assay that allows determination of the quantitative level of each variant in three cellular fractions; e.g., total 5S rRNA, 50S ribosomal subunits, and 70S ribosomes.

Instead, from whatever cause, CIN is directed towards solutions to environmental stresses when it arises, which would then account for the conditional variant expression of aneuploidy in cellular contexts.