Sentence examples for variants have so from inspiring English sources

Despite remarkable progress in technology, only a few associated genetic variants have so far been identified, strongly indicating the need for larger global studies that investigate both common and under-represented rare variants to develop new approaches to combat the disease.

Even if they could be identified, it is unlikely that substantially large genetic effects for other cancers would exist, if the tagging variants have so consistently null effects.

Unlike AMELX, however, no disease causing genetic AMBN variants have so far been reported.

Approximately 120 distinct missense variants have so far been uncovered within the BRCA1 BRCT repeats through breast cancer screening.

For some of these XLID genes, only very few families with pathogenic variants have so far been reported, suggesting that mutations in these genes are very rare.

Nine KPC variants have so far been described (KPC-2 to KPC-10; KPC-1 and KPC-2 are identical) in different parts of the world; variants of KPC-1/2 differ by, at most, two amino acid substitutions [ 1, 5, 6, 16, 21, 22].

The yield of MC4R testing in clinical diagnosis and treatment of obesity is at present undefined since the relatively low prevalence of MC4R pathogenic variants in the general population, along with the high number of sequence variants, has so far compromised the devising of systematic controlled intervention studies.

Although the identification of common breast cancer risk variants has so far had little clinical impact, recent studies pre-COGS demonstrate that it may be possible to use carefully designed SNP genotyping panels to augment breast cancer risk models for high-risk populations such as those with familial breast cancer or to predict contralateral breast cancer risk.

The results for the XRCC3 Thr241Met variant have so far been not been conclusive: variant carriers was found to have increased risk of bladder and breast cancer and malignant melanoma [ 30- 32], whereas in a previous study of ours no association with this marker and bladder cancer was demonstrated [ 8].

PAMPA and its variants, however, have so far only been tested in simulations, a common approach in wireless protocol research.

Furthermore, the genetic variants that have so far been studied are present in the introns rather than in the coding regions.