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All three clusters are fully engaged in these variants, generating a three-fold higher binding affinity for IL-4Rα.
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From the application source-code, Pure::variants generates a feature model, that specifies the features found in the application, as well as a family model, which defines the components that implement these features.
Therefore, under high mutation rates these variants generate a better adapted cloud of mutants.
Linkage analysis incorporating these variants generated a maximum multipoint LOD score of 3.0.
Coulter et al conducted a retrospective chart review of 1792 children who received CMA and found that abnormal variants generated a higher rate of recommendation for clinical action (54%) compared with variants of possible significance (34% P=0.01).
Both ECFP variants generate an ECFP feature for each possible center atom and iteration.
Interestingly, each variant generates a specific distribution of protein assemblies in the cell.
The majority of variants (21/39) led to non-synonymous amino acid changes, whilst 1 variant generated a stop codon at position 8630 bp.
As it is stated above, the variant generates an Ets-1 consensus binding sequence in PAI-1 promoter gene with an increase in the transcription rate [ 33].
Palladin exists in all vertebrates as multiple size variants generated from a single gene that possesses alternative promoters, i.e. a "nested gene".
Maximum number of splice variants generated from a protein kinase gene is 12.
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