Sentence examples for variants ever from inspiring English sources

However, this NumtS was still predicted to differ by six nucleotide substitutions from modern mtDNA, which significantly exceeded the number of variants ever seen on single reads within our dataset.

If genotyping for low penetrance risk variants is ever to be implemented as a cost-effective public health strategy, it will be important to understand the implications of genetic variants on tumour biology and treatment options as well as for risk across the entire population.

Of this list, a hundred or so are synthetic cannabinoids written in chemist's hand – thus, one hundred or so are substances that once rendered illegal will force K2 manufacturers to change the chemical ingredients for products currently on the market, 100 existing variants of an ever-increasing number barred.

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Large-scale clinical sequencing could provide a pool of thousands of new genomes for GWASs that could discover variants that have ever-smaller effect.

Subjects with each of the three possible genotypes (unless no homozygous variant subjects have ever been identified) for each SNP were confirmed by sequencing and included on each genotyping tray.

44 Moreover, any association between a chromosomal region, a specific gene locus, or a single gene variant should, if ever possible, be replicated in one or more separate patient and control cohorts, 10 although differences in ethnic background, treatment procedures, environmental factors, and socioeconomic influences may weaken or even hide any significant findings.

Newly found genetic variants are included in ever more extended genetic profiles.

For example, the OR associated with three or more GST variants was 1.18 among ever smokers (95% CI, 0.82 1.69) but was 1.44 among never smokers (95% CI, 0.97 2.14).

Thus, BRM-741 and BRM-1321 may be germline genetic variants relevant in both ever-and never-smokers, as well as across different cancers (lung, head and neck) and histological subtypes (adenocarcinoma, squamous cell carcinoma).

An elaborate and poorly understood mechanism of coordinated silencing of the VAR genes is combined with rare epigenetic switches to other variants to confer an ever-shifting antigenic makeup.