Sentence examples for variants either in from inspiring English sources

Indeed, with this strategy a variety of genetic variants, either in the same gene or in multiple genes, can be introduced into a single cell line so that they are on the same genetic and epigenetic background (Ding et al., 2013).

To address this issue we tried to express these IGF1R variants either in the presence of an IGF1R kinase inhibitor or in the context of kinase-inactivating point mutations.

Intriguingly, none of the variants, either in the nuclear or mitochondrial genome, contribute to the risk of MDD, despite the fact that the genetic correlation between MDD and the amount of mtDNA is 0.46.

DNA can then be genotyped to detect variants either in specific known genes (e.g., genes with a known involvement in sweet taste) or at a certain location along a chromosome that is predicted to harbor a gene involved in sweet taste.

Analysis was performed by adding known disease variants to either in-house exomes or 1000 Genome Project exomes and with and without the appropriate inheritance model for the disease being tested.

These variants either result in loss of a potential ESE (n = 182), reduced score for an ESE (n = 48), or an increased score (n = 38).

Very recently, Mahachie et al. reported that three strongly-correlated FCER1A polymorphisms were significantly associated with total and specific IgE levels as well as with allergic sensitization, suggesting that FCER1A variants, either alone or in combination, influence IgE levels and act synergistically to influence eczema risk [25].

In order to discover the underlying bona fide causal SNVs, researchers are increasingly adopting in silico functional analyses to prioritize candidate variants, either incorporating this information in the mapping algorithm a priori2,3,4,5, or using it as a filter a posteriori in empirical studies6,7,8,9.

The existence of additional variants (either alleles or paralogs) in the larger I. ricinus species may be investigated on specimens captured in the field or on specimens from other laboratory colonies.

A wide range of HPs was obtained for all 900 ground sample plots in all variants either for individual variables as well as for their intersections.

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