Sentence examples for variants develop from inspiring English sources

It is a challenge to develop direct-acting antiviral agents that target the nonstructural protein 3/4A protease of hepatitis C virus because resistant variants develop.

Understanding the environments in which low-abundance drug-resistant variants develop, how they evolve and impact treatment response are important areas that require further investigations.

[2], [3] The effect of more common variants is generally much less potent than that of rare variants, and as a result, for example, not all carriers of ABCC8 variants develop diabetes.

It is noteworthy that flies expressing the RhCC or RhLAL variants develop smaller eyes compared to the RhΔct flies, which showed a normal morphology (Fig. S1) as well as a perfect fluorescent pseudopupil (data not shown).

Nevertheless, not all carriers of the high risk class II variants develop the disease.

However, importantly, not all African Americans with two high-risk variants develop incident [ 10] or progressive CKD [ 7], suggesting that a "second hit" may be required.

This means that almost all of the rare variants developed after the three populations had split apart.

Bacteriocin variants developed by genetic engineering and novel bacteriocins with broader inhibitory spectra offer new biotechnological opportunities.

All the MCC-KF variants developed in this paper are demonstrated to outperform the previously proposed MCC-KF version in two numerical examples.

Further, since it is possible to utilize the proposed framework as an underlying platform to design more dimensionality reduction variants of LPP, fourteen new variants developed from GMFLLM are approached and investigated in the experiment.

Unlike continuous or pulse exposure to high concentrations of chemotherapeutic drugs which yield high resistance and often cross resistance, most variants developed here displayed low level resistance to the selecting drug with slight cross-resistance.