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Yet, spontaneous appearance of genetic and epigenetic variants contributes to the phenotypic diversity of the individual cultures.
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Many studies have demonstrated that germline variants contribute to the aetiology of breast cancer.
Advances in human genetics have made the identification of genetic variants contributing to these traits feasible.
Mek N, Martin HC, Rice DL, et al. Common genetic variants contribute to risk of rare severe neurodevelopmental disorders.
The algorithms required to identify the variants contributing to disease risk have only more recently become sophisticated enough.
Empirical evidences suggest that both common and rare variants contribute to complex disease etiology.
It has been postulated that lower-frequency variants contribute to the remaining heritability.
Overall, we demonstrate that rare variants contribute to large gene expression changes across tissues and provide an integrative method for interpretation of rare variants in individual genomes.
Behravan, H. et al. Machine learning identifies interacting genetic variants contributing to breast cancer risk: a case study in Finnish cases and controls.
Texture measurements suggest that preferential orientation of martensite variants contributed to the enhanced MCE in the stress-assisted thermally cycled state.
Inability to replicate many results has led to increasing scepticism about the value of simple association study designs for detection of genetic variants contributing to common complex traits.
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