Exact(2)
This outcome potentially could be due to the diminishing returns, in terms of representative variants, contributed by each additional haplotype in the reference panel.
The proportion of discordant and unique LoF, missense and synonymous variants contributed by each geneset reaveal large differences dependent on the reference gene annotation used (Additional file 12: Figure S8).
Similar(58)
Today, we have a variant contributed by Patrick Vennebush, the author of the book Math Jokes 4 Mathy Folks and its extended online blog.
These novel variants contribute to GBM by rendering the ETC.
A role for CLU in AD pathology has long been suspected, solidified by the identification of variants contributing to AD risk by multiple independent GWAS [ 103].
For example, the Iceland-based deCODE study has been successful in identifying rare variants contributing to complex traits by leveraging these characteristics of population isolates in conjunction with extended genealogical information for a variety of complex traits (including prostate cancer, Alzheimer's disease, gout and serum uric acid levels) (33– 33).
Considering the number of H3-like genes in each species may affect the histone concentration; it is tempting to hypothesize that H3-like variants contribute to control gene expression by regulating NRL.
Genome-wide association studies (GWAS) make it possible to identify common variants contributing to such polygenic risk by the use of DNA microarrays to detect common single nucleotide polymorphism (SNPs).
These studies define specific molecular mechanisms and cellular pathways that, when perturbed by multiple gene variants, contribute to neuronal disease or dysfunction.
The mechanisms by which certain genetic variants contribute to higher body mass are still largely unclear.
No evidence was found that pfap2-mu variants contribute to the slow-clearance phenotype exhibited by P. falciparum in Cambodian patients treated with artesunate monotherapy.
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