Sentence examples for variants confer a from inspiring English sources

There was no evidence that other classes of ATM variants confer a risk of breast cancer [ 8].

The 18 breast cancer susceptibility variants confer a polygenic variance of 0.121 and account for approximately 8.4% of the familial risk of breast cancer.

However, given the relatively modest odds ratios seen recently with common polymorphisms, it is very likely that rare variants confer a substantial risk or protection from disease.

In the last decade, it has become clear that the search for high-penetrance genes, whose variants confer a very high excess risk to carriers, has not been yielding important results as it did in previous years.

It is important to note that in the GWAS in asthma and other allergic diseases most single variants confer a very modest odds ratio of 1.1 1.3 to develop disease; however, this has also been observed in other complex disorders.

If certain SDHA variants confer a selective advantage against 3-NPA poisoning by affecting gene expression levels, protein translation efficiency, and/or the binding affinity for 3-NPA, then such variants may provide a survival advantage for their carriers against 3-NPA poisoning.

In all cases, the minor allele led to a decrease in migraine risk (beta coefficient = 0.286 0.315), suggesting that common gene variants confer an increased risk of migraine in the Norfolk pedigree.

Moreover, pooling data from all three studies provide no evidence that variants confer an increased risk of uveal melanoma.

We performed this study to determine whether germline MC1R variants confer an increased risk of uveal melanoma.

To investigate if other CHEK2 variants confer an increased risk of breast cancer, we have screened an affected individual with breast cancer from 68 breast cancer families.

Together, these observations suggest that the three common variants confer an association signal derived from a common source, with rs2282679 exhibiting the strongest association with 25(OH D levels.