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This prevents the influence of any particular rare variant from becoming too large and keeps the grouped rare variants coefficient on the same scale as the coefficients for the common variants.
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With some modifications, the above algorithms can be directly extended to the infinite-interval problem and the variant coefficient ODEs problem.
A second variant in DNMT1 (35433A>G; rs2162560) was measured in the ABC1936 cohort but this was found to be highly reciprocally correlated with the DNMT1 21220C>T variant (coefficient = −0.85; p<0.001) and therefore was not measured in the larger LBC1936 and dropped from the study.
Feng proposed a multi-objective vector evaluated PSO with time variant coefficients for outlier identification in power systems [34].
Due to the anisotropy in shaft and bearings, the motion is governed by differential equations with periodically time-variant coefficients.
The architecture is completely modular and expandable, and includes advanced features such as non-linear templates, time-variant coefficients or multi-layer structure.
Therefore the equation of motion contains terms with time variant coefficients and is impossible to solve without recourse to specialised methods.
A general system model is introduced by describing the restoring forces as bilateral spring-dampers with time-variant coefficients, which are estimated as augmented states.
In contrast, killing increased with expression intensity of the MICA-129Val variant (regression coefficient 0.1257, P < 0.0001 for interaction between MICA-129 variant and MICA expression intensity, two-way ANCOVA).
In contrast, when cells were differentiated, the profiles were more diverse, depending on the variant (correlation coefficient 0.79 0.98; Additional file 2: Table S7), indicating that the overexpressed specific variants have the potential to alter gene regulation during differentiation, as do H3.1 and H3.3 [ 10].
We define a variant, level coefficient (LC), to describe the weight of the information contained with a GO term.
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