Sentence examples for variants changing the from inspiring English sources

However, we observe that there are polymorphic variants that have very low substitution scores, especially variants changing the physicochemical properties of amino acids.

rs78378222 localises within the 3′ untranslated region of TP53 with the risk variant changing the AATAAA polyadenylation signal to AATACA (Stacey et al, 2011).

Only variants potentially changing the protein sequence were used for further analysis; intronic, UTR and synonymous mutations were removed.

Additional "torsionally unrestrained" and "torsionally restrained" sub-variants of each building variant were obtained by changing the mass distribution, while total mass sum remained unchanged.

Bayesian integration with in silico predictions of pathogenicity increased the proportion of correctly classified variants to 87%, without changing the discordance rate.

Plasmids encoding proteolytically inactive variants were obtained by changing the codons for the active-site serine residues to alanine with the QuikChange II point mutagenesis kit (Stratagene).

This involves changing the variant surface glycoprotein (VSG) coat that surrounds the parasite on a regular basis in order to remain one step ahead of the immune system of its host: while the immune system looks for invaders wearing a particular coat, the parasites are spreading through the host in a completely different coat.

Scenario 2 explores the maintenance of segregating variants and the impact of changing the survival advantage (s h ) and trade-off (s p ) of the B allele in worms.

In the previous study, mutations were filtered based on dbSNP build 130 for novel variants and only nonsynonymous (mutations changing the amino acid composition of the protein), nonsense (mutations resulting in either a gain or loss of a stop codon) or essential splice site variants (mutations located within two bases of the intron/exon boundary) were considered.

As a result, changing the boosting variant is considered a minor modification since the architecture of the cascade detector should stay intact.

Variant models are easily generated by changing the geometric and material features using the constraints between them.