Sentence examples for variants causing the from inspiring English sources

Tested on 429 of the most significant functional variants causing the largest changes of gene expression in the GTEx dataset55 (eSNVs), even the best-performing method failed to make correct predictions in 77% of the cases (Fig. 5a, Supplementary Table 2).

These dinucleotides are known to be crucial for the splicing mechanism and SNPs at these positions are usually considered to be regulatory variants causing the observed changes.

Strong [ PSI+] variants suppress ade1-14 mutation better than weak [ PSI+] variants, causing the former to be white and the latter pink on complete media.

Because of the phenotype-driven selection of the Lyon strains from a common SD ancestor, it is likely that divergent haplotypes arising from artificial selective sweeps will contain variants causing the phenotypic differences between the strains.

All sequences recovered from R. norvegicus rats from the Bayannaoer District belonged to cluster D, suggesting that SEOV variants causing the HFRS outbreak in the Bayannaoer District are genetically very close to those from the Huhehaote District.

Model 2: The presence of one or more causative variants caused the same shift of phenotypic mean.

There is no one gene (or several) whose particular variants "cause" the disease.

Gyawali et al. [ 18] also examined whether rs3813034 is itself the variant causing the observed SLC6A4-expression differences.

In conclusion, our data do not support a role of HTR2A and TPH2 genes in ADHD, but for HTR2A we may not have captured the complete genetic variability and we may have missed the genetic variant causing the susceptibility for AP.

And if a large percentage of people with the variant did not develop the condition, scientists felt they could conclude that the behavior related to that variant caused the change in risk for the other condition.

The associated variant causes the amino acid change of Arg-Try, preventing PTPN22 interaction with CSK [ 86, 87].