Sentence examples for variants causing severe from inspiring English sources

This inevitably leads to exclusion of some variants causing severe autosomal dominant disease.

As ETEC F4ab, F4ac and ETEC F18ac are three important ETEC variants causing severe diarrhoea in newborn and/or weaned pigs [ 20, 21], we paid special attention to their respective and common influences on IPEC-J2 cells.

Class II variants cause severe enzyme deficiency (< 10% of normal activity).

Functional analyses of the mutant transporters showed that two of the four identified variants cause severe or moderate loss of CAT-3 function due to altered protein stability or abnormal trafficking to the plasma membrane.

Together, our report described the detailed investigation (clinically and experimentally) of this widespread outbreak of PRRS in China and identification of a new PRRSV variant, causing severe disease in pigs including the adults.

Two families presenting with a current at-risk pregnancy were then studied prospectively, and a molecular genetic diagnosis was obtained in both families through the identification of GLE1 and RYR1 variants causing a severe form of fetal akinesia syndrome with arthrogryposis.

Most of the key antigenic drift variants which caused severe epidemics in Singapore also caused epidemics elsewhere (Table 2).

We previously identified rare functional coding variants that cause severe early-onset monogenic forms of obesity in American Indians.

"It's causing severe mental health problems.

Genetic variants causing absence, or severe reduction of UGT1A1 activity lead to mild forms of unconjugated hyperbilirubinemia, Gilbert syndrome (GS) and CNS-II, or a severe CNS-I form [ 8, 9].

Because the new variant does not cause severe clinical disease, including death, the novel virus is a potential vaccine candidate that could protect the US swine industry from the infection caused by the virulent strain of PEDV currently circulating in United States.