Sentence examples for variants at all from inspiring English sources

Moreover, a genetic risk score analysis combining lead variants at all 7 loci in 22,233 coronary artery disease cases and 64,762 controls showed an association of the alleles associated with shorter LTL with increased risk of coronary artery disease (21%95%5% confidence interval, 5 35%) per standard deviation in LTL, P = 0.014).

The patients for whom tree samples were available showed subsequent replacements of the main viral QS by new variants at all timepoints.

Thus, we propose that the bottlenecked Père David's deer has lost the more powerful ancestral MHC class II haplotypes, which may have contained variants at all nine MHC class II loci (or even more).

Therefore, when used with PCR amplicon sequencing data with a median read depth above 500x, Strelka and MuTect can call variants at all allelic fraction levels, whereas NaiveSubtract, VarScan2, and SomaticSniper provide less sensitivity for calling somatic SNVs of low allelic fraction, at least when using their default settings.

Complex cancers, for instance, may involve hundreds of genetic variants; looking at all the papers on all of them together, she says, can mask actual findings and weaken the statistical strength of the correlation.

ACE can be readily applied to diverse species including animals and plants, making it a broadly useful tool for use in eukaryotic population-based resequencing projects, particularly for assessing the joint impact of all variants at a locus.

Our study suggests full deep sequencing to identify all variants at a locus will be critical to distinguish between genuine allelic heterogeneity and artefacts that appear as evidence of separate association signals.

The apparent stability was monitored by reversible urea-induced equilibrium unfolding transitions for all five variants at a series of different protein concentrations.

The genetic model that underpins synthetic association (allelic heterogeneity caused by several low-frequency variants with larger effects than commonly seen in GWAS) is highly tractable by linkage analysis, which combines information from all causal variants at a particular locus.

Each Two-Temperature LATE-PCR endpoint assay uses a single mismatch-tolerant probe to detect both allele-specific sequences at an upper temperature and the totality of all sequence variants at a lower temperature.

The new research suggests that the roughly 25percentt of Caucasians who have inherited two copies of the "risk variant" have a 40 to 60percentt increased risk of heart disease, as compared with someone who doesn't carry the variant at all.