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These facts may explain the improved performance when classifying RET variants as compared to generalized prediction tools available on-line.
Outbreaks associated with GII.4 variants as compared to non-GII.4 variant were significantly more common in the settings of hospital acute care (p<0.01, Chi square test with Bonferroni correction) while outbreaks associated with non GII.4 variants were significantly more common in the settings of school and community social events (p<0.005, Fisher Exact test with Bonferroni correction).
Results for each of the eight series that were tested are shown in Figure 1A and 1B. Figure 1C shows box plots which compare the relative level of IDE transcript in carriers of these two variants as compared to non-carriers.
The PGx variants, as compared to disease-associated variants, have not been investigated as deeply.
In the undiagnosed individuals (10/23; 43%) we detected a significant enrichment of potentially pathogenic variants as compared to controls.
PCR was performed to determine the proportion of C1/C2 variants as compared with C3 variants in the SUM-52PE cell line.
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During a hyperinsulinemic glucose clamp study, the rate of glucose infusion required to maintain euglycemia in the last hour of the clamp was somewhat higher in the 2 carriers of the R225W variant as compared to 2 closely matched controls but did not reach a nominal standard of significance (7.3±0.8 vs. 5.4±2.4 ml/kg/min, p = 0.16).
To this aim, it is currently ongoing a prospective study in mCRC patients treated with first-line FOLFIRI and bevacizumab, designed with the aim of revealing a 40% risk reduction in PFS bearing VEGF -1498 C-variants as compared to those carrying -1498 T/T genotype.
Gouvali and Boudolos also reported greater vGRF in the traditional variant, as compared to the modified [ 25].
Among 38 patients with aggressive NHL, 14 (37%) were carrying the bFGF G variant as compared to 23 out of 122 (19%) healthy individuals (OR = 2.51, P = 0.038) (Table 3).
Additional amplicons were detected in the green variant as compared to the orange variant (Additional file 4: Figure S3b), demonstrating the possibility of transposase movement to a new location in the endosymbiont genome.
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alternatives as compared
versions as compared
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ways as compared
implementations as compared
derivatives as compared
iterations as compared
modifications as compared
mutant as compared
variation as compared
variants as reported
variants as suggested
variants as damaged
variants as opposed
variants as characterized
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