Sentence examples for variants are implicated from inspiring English sources

Although it may become technically possible to edit DNA accurately at multiple loci, it is unlikely that we will learn anytime soon what exactly needs to be programmed when tens or hundreds of variants are implicated.

This is not particularly striking, as many researchers might have expected that a large number of variants are implicated from the polygenic model for complex diseases.

Besides HNF1B, other gene loci have started appearing where variants are identified that modulate susceptibility to both T2D and some malignancy, e.g. prostate cancer for the JAZF1 locus gene [11], [42] and melanoma for the CDKN2A locus [43], although different, unlinked variants are implicated in the susceptibility to the malignancy and T2D, respectively.

37, 38 CRHR1 variants are implicated in human depression 39– 42 and antidepressant response.

90, 91 Some MC4R variants are implicated in weight regulation and BMI.

Certainly we can hope for a more complete picture of etiology as multiple genetic variants are implicated in related phenotypes.

Not sure about the premise of the Indy's news story, especially given that several gene variants were implicated in autism barely a year ago and the results published in Nature and the Annals of Human Genetics.

More recently, certain PON1 polymorphic variants were implicated as risk factors for other chronic inflammatory diseases, including RA and types 1 and 2 diabetes [ 44, 45].

Although the present study included tagging SNPs in most currently known miRNA biogenesis pathway genes, future studies should investigate the comprehensive list of genetic variants in miRNA genes and target binding site in 3'-untranslated 3'-untranslatedstand how theiregiongulatoon of miRNA network caunderstandtially by thowgenetheirariants is implicatederegulationcancer profnosis.

The association of MBL levels with skin involvement and disease activity was even more pronounced in diffuse SSc patients, lending support to the hypothesis of SSc being a heterogenous disease with different genetic variants being implicated in specific SSc subtypes [ 42].

This genetic variant is implicated in insulin secretion, which may be the explanation for its association with T2D [ 73, 74].