Sentence examples for variants are fixed from inspiring English sources

NAHR, in turn, is one mechanism by which de novo structural variants are fixed in the genome.

In the first, some variants are fixed by positive selection to compensate deleterious mutations in other epistatically interacting positions.

As the authors argue earlier in the paper, it is neutral evolution in the functionally "static" period that promotes effective search, then new variants are fixed through a rapid bout of selection.

Such studies should also avoid distortions caused by factors occurring later in life (such as the onset of disease) because genetic variants are fixed at conception. 8 Hence, mendelian randomisation analyses should confer certain design advantages akin to those in randomised trials.

Our multiple regressions with dN and dS furthermore suggest that these trends may be driven largely by variation in dS, instead of dN, perhaps related to variation in life history traits which affect the rate at which neutral variants are fixed [ 49, 50].

The input data of all variants were fixed to "paste file content" menu before the map was drawn.

Our simulations show that statistical power of testing association decreases as gene elongates, though the proportion of causative variants is fixed.

Four non-synonymous variant sites were found to be natural polymorphisms, as the variants were fixed in some genomes but not in others.

Not only have useful variants been fixed into the original domesticated pools, but additional genes that may be useful for plant breeding have lost their diversity through genetic drift.

For instance, the variation of predicted risk scores for each individual is proportionally related to the number of causal variants, and the accuracy of the predicted disease status decreases with the increase of the number of causal variants when the relative proportion of variance explained by causal variants is fixed [ 2, 3].

For many of the positions appearing as Simple SNPs in our data, it's likely that, in the process of homogenisation associated with inbreeding, opposing allelic variants were fixed in the inbred lines (eg. AT[O]AT[P'] homogenised to TT[O]TT[P'] in one inbred line and to AA[O]AA[P'] in another.