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Additionally, the results of other controlling variants are consistent with our expectations as well, which further shows that our results are robust.
Our findings at the DNA sequence level for these variants are consistent to those reported previously [9], [10].
Thus existing functional assay results for these three variants are consistent with their being either neutral or at most weakly pathogenic.
Nonetheless, the frequencies of missense and synonymous variants are consistent with those reported in large databases such as 1000 Genomes [ 44], Exome Aggregation Consortium [ 45] and Exome Variant Server [ 46].
It turned out that all of the rs IDs of the 175 variants are consistent with those given by SNPTracker, suggesting SNPTracker retrieved the rs IDs even more comprehensively than dbSNP Batch Query (2005).
It has been reported that there are two Dlic molecules per dynein motor (King et al., 1996; Trokter et al., 2012) and hence our estimates of Dlic copy number on h RNA variants are consistent with 3.36 ± 0.21, 2.18 ± 0.16, and 6.92 ± 0.33 dynein motors associated with hWT, hΔLE, or hSL1x3 RNPs, respectively.
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The direction of effect for both variants is consistent across each individual sample set (Table 2).
In this respect, the behavior of type I and II-associated variants is consistent with previous studies [27].
Relative protein expression levels between these variants were consistent as protein accumulated during growth phase and were maintained in stationary phase (data not shown).
The absence of a protein concentration dependence for refolding under any conditions for all of the variants is consistent with the rate-limiting unimolecular monomer folding reaction observed for SOD1 [20] [21], [21].
The multiple interspersed phylogenetic positions of VP4/VP2-encoding sequences from HRV-Ca and HRV-Cc variants is consistent with multiple inter-species recombination events in the evolutionary history of human rhinoviruses.
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