Sentence examples for variants and structural from inspiring English sources

The contribution of rare variants and structural variations to complex diseases is largely unexplored in the literature.

Small variants and structural variants represent different types of genomic variation.

Minor variants and structural variants represent different types of genomic modifications.

Some features, such as physico-chemical property of amino acid variants and structural information, were used successfully before [ 5, 24].

We counted the number of small variants and structural variants among these genotypes and we also estimated the divergence between each genome with the peach reference genome.

It is also worth noting that the position of an editing event may result in truncated products, splice variants, and structural changes.

Two different sources of variants were used: (1) single nucleotide variants (SNV) and structural variants (SV) from genome sequencing (2.1) and (2) SNVs and SVs called in an initial alignment round of the RNA-Seq reads to the TAIR10 reference genome with PALMapper (relevant parameters: -M 4 -G 4 -E 6 -I 25000 -NI 1 -S).

In addition, other classes of variation, such as short insertion deletion variants (indels), as well as copy number variants (CNVs) and structural variants (SVs), are even more difficult to detect using high-throughput sequencing.

We identified small nucleotide variants (SNVs) and structural variants (SVs) in the LG/J and SM/J strains relative to the reference genome and discovered novel variants in these two strains by comparing their sequences to other mouse genomes.

Altogether, we identified more than 13 million single-nucleotide variants, indels, and structural variants across these rat strains.

If individuals have different copies of a given duplicon in homologous chromosomes, that is, if they are heterozygous for structural variants and these structural variants contain genes, it is possible that certain alleles appear to be differentially expressed.