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The aim of our study was to assess the association of common sequence variants, and selected interactions, with HDL-c plasma levels.
From the ILC patient group, we included classic and pleomorphic variants and selected patients with an IHC report of TN as previously described.
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Additional features are provided for referencing previous findings about known variants and their loci, including previously cataloged SNPs, information about disease SNPs, and Gencode gene annotation, which contains a large number of non-coding RNAs.> A user uploads a list of genetic variants and selects the features to be integrated through a user-friendly Web interface.
This procedure was executed separately for each variant and selected structural variables, as well as for their intersection parts.
The DNA expression-construct pCMV-HA-CA-MEK5 [ 41] was used to derive MEK5 over-expressing variants of MCF-7 (N variant) cell line and selected with G418 (Gibco, Paisley, UK).
Therefore, to investigate the role of the opaque and transparent phenotypes in biofilm formation, pure transparent and opaque colony variants were used and selected as described in Experimental procedures.
Using G2 as a scaffold, we constructed phage-displayed libraries of FHA1 variants and affinity selected for variants that bound selectively to five pT peptides.
Often associations between selection signatures and selected variants for complex traits is assumed even though this is rarely (if ever) tested.
To conduct this assay, cells were first transduced with the tet-responsive vector carrying the MyoD variant of interest and selected in puromycin to obtain a pure population.
In another, called directed evolution, scientists mutated an enzyme into many variants and then selected the one that best fit their needs.
Upon submitting the input variants and the selected genomic features, the data integration job is added to a queue on the server side.
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