Sentence examples for variants and increased from inspiring English sources

Associations of IRF5 (interferon regulator factor 5) genetic variants and increased SLE risk have been highly replicated [25].

The close relationship between genetic variants and increased susceptibility to bronchial obstruction has been repeatedly reported [ 26, 27].

However, the importance of the original SNP (Val158Met) has been disputed [ 50], and the link between the COMT variants and increased pain perception does not replicate across populations.

Of interest, a recent follow-up study of 288 superficial bladder cancer patients showed no association between XPC-PAT or Lys939Gln variants and increased risk of tumour recurrence (Gu et al, 2005).

A recent study reported a significant association between a genetic score based on multiple diabetes-predisposing variants and increased risk of coronary heart disease (CHD) in a general population (2).

The discovery of polymorphisms in MMP promoters that alter gene expression has revealed strong associations between these genetic variants and increased susceptibility to the development of malignancies and other diseases (Henney et al, 2000; Ye, 2000).

In our study, we observed no association between the examined variant and increased family history.

Our analyses based on a recessive transmission model suggested an association between the BRCA2 N372H variant and increased MBC risk in men younger than 60 years.

The cancer risk increased as the number of variants rose and increased substantially when men had four or five of the variants.

Compared to previously described variants (available in WormBase), our effort uncovered twice as many single nucleotide variants (SNVs) and increased the number of small InDels almost 20-fold.

Variants with decreased stability of the II and/or III domains developed in three patients, increased stability variants appeared in another three, and in one patient variants with decreased and increased stability developed simultaneously.